1wav
From Proteopedia
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- | [[Image:1wav.gif|left|200px]] | + | [[Image:1wav.gif|left|200px]] |
- | + | ||
- | '''CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN''' | + | {{Structure |
+ | |PDB= 1wav |SIZE=350|CAPTION= <scene name='initialview01'>1wav</scene>, resolution 2.5Å | ||
+ | |SITE= | ||
+ | |LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=IPH:PHENOL'>IPH</scene> | ||
+ | |ACTIVITY= | ||
+ | |GENE= | ||
+ | }} | ||
+ | |||
+ | '''CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN''' | ||
+ | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
- | 1WAV is a [ | + | 1WAV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WAV OCA]. |
==Reference== | ==Reference== | ||
- | Molecular replacement study on form-B monoclinic crystal of insulin., Ding J, Wan Z, Chang W, Liang D, Sci China C Life Sci. 1996 Apr;39(2):144-53. PMID:[http:// | + | Molecular replacement study on form-B monoclinic crystal of insulin., Ding J, Wan Z, Chang W, Liang D, Sci China C Life Sci. 1996 Apr;39(2):144-53. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8760462 8760462] |
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
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[[Category: phenol]] | [[Category: phenol]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:54:31 2008'' |
Revision as of 12:54, 20 March 2008
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, resolution 2.5Å | |||||||
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Ligands: | and | ||||||
Coordinates: | save as pdb, mmCIF, xml |
CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN
Overview
The form-B monoclinic insulin crystal was obtained from the sodium citrate buffer with 1% zinc chloride, keeping phenolic content between 0.76% and 1.25%. Its space group is P2(1), cell constants are: a = 4.924 nm, b = 6.094 nm, c = 4.818 nm, beta = 95.8 degrees. There are 6 insulin molecules which form a hexamer. The initial phase was obtained by using rotation function program of X-PLOR program package and molecular packing program of our laboratory. The molecular model was chosen from 4 zinc bovine insulin hexamer. After the preliminary refinement by using the macromolecular rigid body refinement technique, the molecular model was further refined and adjusted by using the energy-minimizing stereochemically restrained least-squared refinement on the difference Fourier maps. The final R-factor is 22.4% at 0.3 nm resolution, the r.m.s. deviations from standard bond length and bond angle are 0.0022 nm and 4.7 degrees, respectively.
About this Structure
1WAV is a Protein complex structure of sequences from Sus scrofa. Full crystallographic information is available from OCA.
Reference
Molecular replacement study on form-B monoclinic crystal of insulin., Ding J, Wan Z, Chang W, Liang D, Sci China C Life Sci. 1996 Apr;39(2):144-53. PMID:8760462
Page seeded by OCA on Thu Mar 20 14:54:31 2008
Categories: Protein complex | Sus scrofa | Chang, W R. | Ding, J H. | Liang, D C. | Wan, Z L. | IPH | ZN | Hormone | Insulin | Phenol