2o9i

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Revision as of 12:38, 7 January 2013

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Template:STRUCTURE 2o9i

Crystal Structure of the Human Pregnane X Receptor LBD in complex with an SRC-1 coactivator peptide and T0901317

Template:ABSTRACT PUBMED 17215127

About this Structure

2o9i is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Xue Y, Chao E, Zuercher WJ, Willson TM, Collins JL, Redinbo MR. Crystal structure of the PXR-T1317 complex provides a scaffold to examine the potential for receptor antagonism. Bioorg Med Chem. 2007 Mar 1;15(5):2156-66. Epub 2006 Dec 20. PMID:17215127 doi:10.1016/j.bmc.2006.12.026