1wcd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1wcd.gif|left|200px]]<br /><applet load="1wcd" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1wcd.gif|left|200px]]
-
caption="1wcd, resolution 3.0&Aring;" />
+
 
-
'''CRYSTAL STRUCTURE OF IBDV T1 VIRUS-LIKE PARTICLE REVEALS A MISSING LINK IN ICOSAHEDRAL VIRUSES EVOLUTION'''<br />
+
{{Structure
 +
|PDB= 1wcd |SIZE=350|CAPTION= <scene name='initialview01'>1wcd</scene>, resolution 3.0&Aring;
 +
|SITE=
 +
|LIGAND=
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''CRYSTAL STRUCTURE OF IBDV T1 VIRUS-LIKE PARTICLE REVEALS A MISSING LINK IN ICOSAHEDRAL VIRUSES EVOLUTION'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1WCD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Infectious_bursal_disease_virus Infectious bursal disease virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WCD OCA].
+
1WCD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Infectious_bursal_disease_virus Infectious bursal disease virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WCD OCA].
==Reference==
==Reference==
-
The birnavirus crystal structure reveals structural relationships among icosahedral viruses., Coulibaly F, Chevalier C, Gutsche I, Pous J, Navaza J, Bressanelli S, Delmas B, Rey FA, Cell. 2005 Mar 25;120(6):761-72. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15797378 15797378]
+
The birnavirus crystal structure reveals structural relationships among icosahedral viruses., Coulibaly F, Chevalier C, Gutsche I, Pous J, Navaza J, Bressanelli S, Delmas B, Rey FA, Cell. 2005 Mar 25;120(6):761-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15797378 15797378]
[[Category: Infectious bursal disease virus]]
[[Category: Infectious bursal disease virus]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 27: Line 36:
[[Category: icosahedral virus]]
[[Category: icosahedral virus]]
[[Category: membrane translocation activity]]
[[Category: membrane translocation activity]]
-
[[Category: non-enveloped icosahedral viruses]]
+
[[Category: non-enveloped icosahedral viruse]]
[[Category: transcriptase machinery]]
[[Category: transcriptase machinery]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:42:53 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:55:09 2008''

Revision as of 12:55, 20 March 2008

Image:1wcd.gif


PDB ID 1wcd

Drag the structure with the mouse to rotate
, resolution 3.0Å
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF IBDV T1 VIRUS-LIKE PARTICLE REVEALS A MISSING LINK IN ICOSAHEDRAL VIRUSES EVOLUTION


Overview

Double-stranded RNA virions are transcriptionally competent icosahedral particles that must translocate across a lipid bilayer to function within the cytoplasm of the target cell. Birnaviruses are unique among dsRNA viruses as they have a single T = 13 icosahedral shell, lacking the characteristic inner capsid observed in the others. We determined the crystal structures of the T = 1 subviral particle (260 angstroms in diameter) and of the T = 13 intact virus particle (700 angstroms in diameter) of an avian birnavirus to 3 angstroms and 7 angstroms resolution, respectively. Our results show that VP2, the only component of the virus icosahedral capsid, is homologous both to the capsid protein of positive-strand RNA viruses, like the T = 3 nodaviruses, and to the T = 13 capsid protein of members of the Reoviridae family of dsRNA viruses. Together, these results provide important insights into the multiple functions of the birnavirus capsid and reveal unexpected structural relationships among icosahedral viruses.

About this Structure

1WCD is a Single protein structure of sequence from Infectious bursal disease virus. Full crystallographic information is available from OCA.

Reference

The birnavirus crystal structure reveals structural relationships among icosahedral viruses., Coulibaly F, Chevalier C, Gutsche I, Pous J, Navaza J, Bressanelli S, Delmas B, Rey FA, Cell. 2005 Mar 25;120(6):761-72. PMID:15797378

Page seeded by OCA on Thu Mar 20 14:55:09 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1wcd"
Personal tools