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2kp8

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Revision as of 13:40, 7 January 2013

Image:2kp8.png

Template:STRUCTURE 2kp8

Ligand bound to a model peptide that mimics the open fusogenic form

Template:ABSTRACT PUBMED 20004576

About this Structure

2kp8 is a 3 chain structure with sequence from Escherichia coli. Full experimental information is available from OCA.

Reference

Stewart KD, Huth JR, Ng TI, McDaniel K, Hutchinson RN, Stoll VS, Mendoza RR, Matayoshi ED, Carrick R, Mo H, Severin J, Walter K, Richardson PL, Barrett LW, Meadows R, Anderson S, Kohlbrenner W, Maring C, Kempf DJ, Molla A, Olejniczak ET. Non-peptide entry inhibitors of HIV-1 that target the gp41 coiled coil pocket. Bioorg Med Chem Lett. 2010 Jan 15;20(2):612-7. Epub 2009 Nov 20. PMID:20004576 doi:10.1016/j.bmcl.2009.11.076