2jx3

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m (Protected "2jx3" [edit=sysop:move=sysop])
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[[Image:2jx3.png|left|200px]]
 
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{{STRUCTURE_2jx3| PDB=2jx3 | SCENE= }}
{{STRUCTURE_2jx3| PDB=2jx3 | SCENE= }}
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===NMR solution structure of the N-terminal domain of DEK===
===NMR solution structure of the N-terminal domain of DEK===
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{{ABSTRACT_PUBMED_18227428}}
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{{ABSTRACT_PUBMED_18227428}}
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==Disease==
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[[http://www.uniprot.org/uniprot/DEK_HUMAN DEK_HUMAN]] Note=A chromosomal aberration involving DEK is found in a subset of acute myeloid leukemia (AML); also known as acute non-lymphocytic leukemia. Translocation t(6;9)(p23;q34) with NUP214/CAN. It results in the formation of a DEK-CAN fusion gene.
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==Function==
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[[http://www.uniprot.org/uniprot/DEK_HUMAN DEK_HUMAN]] Involved in chromatin organization.<ref>PMID:17524367</ref>
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:018227428</ref><references group="xtra"/>
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<ref group="xtra">PMID:018227428</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Devany, M.]]
[[Category: Devany, M.]]

Revision as of 20:36, 24 March 2013

Template:STRUCTURE 2jx3

Contents

NMR solution structure of the N-terminal domain of DEK

Template:ABSTRACT PUBMED 18227428

Disease

[DEK_HUMAN] Note=A chromosomal aberration involving DEK is found in a subset of acute myeloid leukemia (AML); also known as acute non-lymphocytic leukemia. Translocation t(6;9)(p23;q34) with NUP214/CAN. It results in the formation of a DEK-CAN fusion gene.

Function

[DEK_HUMAN] Involved in chromatin organization.[1]

About this Structure

2jx3 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Devany M, Kappes F, Chen KM, Markovitz DM, Matsuo H. Solution NMR structure of the N-terminal domain of the human DEK protein. Protein Sci. 2008 Feb;17(2):205-15. PMID:18227428 doi:17/2/205
  1. ↑ Hu HG, Scholten I, Gruss C, Knippers R. The distribution of the DEK protein in mammalian chromatin. Biochem Biophys Res Commun. 2007 Jul 13;358(4):1008-14. Epub 2007 May 21. PMID:17524367 doi:10.1016/j.bbrc.2007.05.019

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OCA

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