1wvo
From Proteopedia
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| - | [[Image:1wvo.gif|left|200px]] | + | [[Image:1wvo.gif|left|200px]] |
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| - | '''Solution structure of RSGI RUH-029, an antifreeze protein like domain in human N-acetylneuraminic acid phosphate synthase gene.''' | + | {{Structure |
| + | |PDB= 1wvo |SIZE=350|CAPTION= <scene name='initialview01'>1wvo</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''Solution structure of RSGI RUH-029, an antifreeze protein like domain in human N-acetylneuraminic acid phosphate synthase gene.''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1WVO is a [ | + | 1WVO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WVO OCA]. |
==Reference== | ==Reference== | ||
| - | Solution structure of the antifreeze-like domain of human sialic acid synthase., Hamada T, Ito Y, Abe T, Hayashi F, Guntert P, Inoue M, Kigawa T, Terada T, Shirouzu M, Yoshida M, Tanaka A, Sugano S, Yokoyama S, Hirota H, Protein Sci. 2006 May;15(5):1010-6. Epub 2006 Apr 5. PMID:[http:// | + | Solution structure of the antifreeze-like domain of human sialic acid synthase., Hamada T, Ito Y, Abe T, Hayashi F, Guntert P, Inoue M, Kigawa T, Terada T, Shirouzu M, Yoshida M, Tanaka A, Sugano S, Yokoyama S, Hirota H, Protein Sci. 2006 May;15(5):1010-6. Epub 2006 Apr 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16597820 16597820] |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: antifreeze protein like domain]] | [[Category: antifreeze protein like domain]] | ||
[[Category: n-acetylneuraminic acid phosphate synthase]] | [[Category: n-acetylneuraminic acid phosphate synthase]] | ||
| - | [[Category: national project on protein structural and functional | + | [[Category: national project on protein structural and functional analyse]] |
[[Category: nmr]] | [[Category: nmr]] | ||
[[Category: nppsfa]] | [[Category: nppsfa]] | ||
[[Category: riken structural genomics/proteomics initiative]] | [[Category: riken structural genomics/proteomics initiative]] | ||
[[Category: rsgi]] | [[Category: rsgi]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:02:07 2008'' |
Revision as of 13:02, 20 March 2008
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
Solution structure of RSGI RUH-029, an antifreeze protein like domain in human N-acetylneuraminic acid phosphate synthase gene.
Overview
The structure of the C-terminal antifreeze-like (AFL) domain of human sialic acid synthase was determined by NMR spectroscopy. The structure comprises one alpha- and two single-turn 3(10)-helices and two beta-strands, and is similar to those of the type III antifreeze proteins. Evolutionary trace analyses of the type III antifreeze protein family suggested that the class-specific residues in the human and bacterial AFL domains are important for their substrate binding, while the class-specific residues of the fish antifreeze proteins are gathered on the ice-binding surface.
About this Structure
1WVO is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Solution structure of the antifreeze-like domain of human sialic acid synthase., Hamada T, Ito Y, Abe T, Hayashi F, Guntert P, Inoue M, Kigawa T, Terada T, Shirouzu M, Yoshida M, Tanaka A, Sugano S, Yokoyama S, Hirota H, Protein Sci. 2006 May;15(5):1010-6. Epub 2006 Apr 5. PMID:16597820
Page seeded by OCA on Thu Mar 20 15:02:07 2008
Categories: Homo sapiens | Single protein | Hamada, T. | Hayashi, F. | Hirota, H. | Ito, Y. | RSGI, RIKEN Structural Genomics/Proteomics Initiative. | Yokoyama, S. | Antifreeze protein like domain | N-acetylneuraminic acid phosphate synthase | National project on protein structural and functional analyse | Nmr | Nppsfa | Riken structural genomics/proteomics initiative | Rsgi | Structural genomic
