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2pf4
From Proteopedia
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{{STRUCTURE_2pf4| PDB=2pf4 | SCENE= }} | {{STRUCTURE_2pf4| PDB=2pf4 | SCENE= }} | ||
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===Crystal structure of the full-length simian virus 40 small t antigen complexed with the protein phosphatase 2A Aalpha subunit=== | ===Crystal structure of the full-length simian virus 40 small t antigen complexed with the protein phosphatase 2A Aalpha subunit=== | ||
| + | {{ABSTRACT_PUBMED_17608567}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/2AAA_MOUSE 2AAA_MOUSE]] The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
[[2pf4]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Simian_virus_40 Simian virus 40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PF4 OCA]. | [[2pf4]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Simian_virus_40 Simian virus 40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PF4 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:017608567</ref><references group="xtra"/><references/> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Simian virus 40]] | [[Category: Simian virus 40]] | ||
Revision as of 06:30, 20 June 2013
Contents |
Crystal structure of the full-length simian virus 40 small t antigen complexed with the protein phosphatase 2A Aalpha subunit
Template:ABSTRACT PUBMED 17608567
Function
[2AAA_MOUSE] The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis (By similarity).
About this Structure
2pf4 is a 8 chain structure with sequence from Mus musculus and Simian virus 40. Full crystallographic information is available from OCA.
Reference
- Cho US, Morrone S, Sablina AA, Arroyo JD, Hahn WC, Xu W. Structural basis of PP2A inhibition by small t antigen. PLoS Biol. 2007 Aug;5(8):e202. PMID:17608567 doi:10.1371/journal.pbio.0050202
