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3cqw

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Revision as of 18:17, 7 January 2013

Image:3cqw.png

Template:STRUCTURE 3cqw

Crystal Structure of Akt-1 complexed with substrate peptide and inhibitor

Template:ABSTRACT PUBMED 18456494

About this Structure

3cqw is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lippa B, Pan G, Corbett M, Li C, Kauffman GS, Pandit J, Robinson S, Wei L, Kozina E, Marr ES, Borzillo G, Knauth E, Barbacci-Tobin EG, Vincent P, Troutman M, Baker D, Rajamohan F, Kakar S, Clark T, Morris J. Synthesis and structure based optimization of novel Akt inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3359-63. Epub 2008 Apr 15. PMID:18456494 doi:10.1016/j.bmcl.2008.04.034

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OCA

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