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2xzz
From Proteopedia
(Difference between revisions)
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| - | + | ==CRYSTAL STRUCTURE OF THE HUMAN TRANSGLUTAMINASE 1 BETA-BARREL DOMAIN== | |
| - | + | <StructureSection load='2xzz' size='340' side='right' caption='[[2xzz]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2xzz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XZZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-glutamine_gamma-glutamyltransferase Protein-glutamine gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.13 2.3.2.13] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xzz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xzz RCSB], [http://www.ebi.ac.uk/pdbsum/2xzz PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | == | + | == Disease == |
| - | [[2xzz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZZ OCA]. | + | [[http://www.uniprot.org/uniprot/TGM1_HUMAN TGM1_HUMAN]] Lamellar ichthyosis;Self-healing collodion baby;Bathing suit ichthyosis;Acral self-healing collodion baby;Congenital non-bullous ichthyosiform erythroderma. The disease is caused by mutations affecting the gene represented in this entry. |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TGM1_HUMAN TGM1_HUMAN]] Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein-glutamine gamma-glutamyltransferase]] | [[Category: Protein-glutamine gamma-glutamyltransferase]] | ||
Revision as of 13:05, 22 October 2014
CRYSTAL STRUCTURE OF THE HUMAN TRANSGLUTAMINASE 1 BETA-BARREL DOMAIN
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