3bxv

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[[Image:3bxv.png|left|200px]]
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==Crystal structure studies on sulfur oxygenase reductase from Acidianus tengchongensis==
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<StructureSection load='3bxv' size='340' side='right' caption='[[3bxv]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3bxv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acidianus_tengchongensis Acidianus tengchongensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BXV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BXV FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene><br>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sulfur_oxygenase/reductase Sulfur oxygenase/reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.55 1.13.11.55] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bxv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bxv RCSB], [http://www.ebi.ac.uk/pdbsum/3bxv PDBsum]</span></td></tr>
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bx/3bxv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Sulfur oxygenase reductase (SOR) simultaneously catalyzes oxidation and reduction of elemental sulfur to produce sulfite, thiosulfate, and sulfide in the presence of molecular oxygen. In this study, crystal structures of wild type and mutants of SOR from Acidianus tengchongensis (SOR-AT) in two different crystal forms were determined and it was observed that 24 identical SOR monomers form a hollow sphere. Within the icosatetramer sphere, the tetramer and trimer channels were proposed as the paths for the substrate and products, respectively. Moreover, a comparison of SOR-AT with SOR-AA (SOR from Acidianus ambivalens) structures showed that significant differences existed at the active site. Firstly, Cys31 is not persulfurated in SOR-AT structures. Secondly, the iron atom is five-coordinated rather than six-coordinated, since one of the water molecules ligated to the iron atom in the SOR-AA structure is lost. Consequently, the binding sites of substrates and a hypothetical catalytic process of SOR were proposed.
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{{STRUCTURE_3bxv| PDB=3bxv | SCENE= }}
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Crystal structure studies on sulfur oxygenase reductase from Acidianus tengchongensis.,Li M, Chen Z, Zhang P, Pan X, Jiang C, An X, Liu S, Chang W Biochem Biophys Res Commun. 2008 May 9;369(3):919-23. Epub 2008 Mar 7. PMID:18329378<ref>PMID:18329378</ref>
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===Crystal structure studies on sulfur oxygenase reductase from Acidianus tengchongensis===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_18329378}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[3bxv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acidianus_tengchongensis Acidianus tengchongensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BXV OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:018329378</ref><references group="xtra"/>
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[[Category: Acidianus tengchongensis]]
[[Category: Acidianus tengchongensis]]
[[Category: Sulfur oxygenase/reductase]]
[[Category: Sulfur oxygenase/reductase]]

Revision as of 21:25, 2 October 2014

Crystal structure studies on sulfur oxygenase reductase from Acidianus tengchongensis

3bxv, resolution 2.70Å

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