This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3bl3
From Proteopedia
(Difference between revisions)
m (Protected "3bl3" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:3bl3.png|left|200px]] | ||
| - | |||
{{STRUCTURE_3bl3| PDB=3bl3 | SCENE= }} | {{STRUCTURE_3bl3| PDB=3bl3 | SCENE= }} | ||
| - | |||
===tRNA guanine transglycosylase V233G mutant apo structure=== | ===tRNA guanine transglycosylase V233G mutant apo structure=== | ||
| + | {{ABSTRACT_PUBMED_23704982}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168] | ||
==About this Structure== | ==About this Structure== | ||
[[3bl3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BL3 OCA]. | [[3bl3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BL3 OCA]. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[TRNA-guanine transglycosylase|TRNA-guanine transglycosylase]] | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023704982</ref><references group="xtra"/><references/> | ||
[[Category: Zymomonas mobilis]] | [[Category: Zymomonas mobilis]] | ||
| - | [[Category: TRNA-guanine transglycosylase]] | ||
[[Category: Heine, A.]] | [[Category: Heine, A.]] | ||
[[Category: Klebe, G.]] | [[Category: Klebe, G.]] | ||
Revision as of 04:12, 18 July 2013
Contents |
tRNA guanine transglycosylase V233G mutant apo structure
Template:ABSTRACT PUBMED 23704982
Function
[TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
About this Structure
3bl3 is a 1 chain structure with sequence from Zymomonas mobilis. Full crystallographic information is available from OCA.
See Also
Reference
- Biela I, Tidten-Luksch N, Immekus F, Glinca S, Nguyen TX, Gerber HD, Heine A, Klebe G, Reuter K. Investigation of specificity determinants in bacterial tRNA-guanine transglycosylase reveals queuine, the substrate of its eucaryotic counterpart, as inhibitor. PLoS One. 2013 May 21;8(5):e64240. doi: 10.1371/journal.pone.0064240. Print 2013. PMID:23704982 doi:10.1371/journal.pone.0064240
