3dks
From Proteopedia
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| - | [[Image:3dks.png|left|200px]] | ||
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{{STRUCTURE_3dks| PDB=3dks | SCENE= }} | {{STRUCTURE_3dks| PDB=3dks | SCENE= }} | ||
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===DsbA substrate complex=== | ===DsbA substrate complex=== | ||
| + | {{ABSTRACT_PUBMED_19389711}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/DSBA_SHIFL DSBA_SHIFL]] Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. It is required for pilus biogenesis. | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3dks]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3dks]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DKS OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:019389711</ref><references group="xtra"/> | + | <ref group="xtra">PMID:019389711</ref><references group="xtra"/><references/> |
| - | [[Category: Shigella | + | [[Category: Shigella paradysenteriae weldin 1927]] |
[[Category: Borg, N A.]] | [[Category: Borg, N A.]] | ||
[[Category: Horne, J.]] | [[Category: Horne, J.]] | ||
Revision as of 05:43, 29 January 2014
Contents |
DsbA substrate complex
Template:ABSTRACT PUBMED 19389711
Function
[DSBA_SHIFL] Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. It is required for pilus biogenesis.
About this Structure
3dks is a 6 chain structure with sequence from "shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927. Full crystallographic information is available from OCA.
Reference
- Paxman JJ, Borg NA, Horne J, Thompson PE, Chin Y, Sharma P, Simpson JS, Wielens J, Piek S, Kahler CM, Sakellaris H, Pearce M, Bottomley SP, Rossjohn J, Scanlon MJ. The structure of the bacterial oxidoreductase enzyme DsbA in complex with a peptide reveals a basis for substrate specificity in the catalytic cycle of DsbA enzymes. J Biol Chem. 2009 Jun 26;284(26):17835-45. Epub 2009 Apr 22. PMID:19389711 doi:10.1074/jbc.M109.011502
