2q8g

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Revision as of 20:49, 7 January 2013

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Template:STRUCTURE 2q8g

Contents 1 Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545 2 About this Structure 3 See Also 4 Reference

Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545

Template:ABSTRACT PUBMED 17683942

About this Structure

2q8g is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Pyruvate dehydrogenase kinase

Reference

• Kato M, Li J, Chuang JL, Chuang DT. Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol. Structure. 2007 Aug;15(8):992-1004. Epub 2007 Aug 2. PMID:17683942 doi:10.1016/j.str.2007.07.001