2qme
From Proteopedia
m (Protected "2qme" [edit=sysop:move=sysop]) |
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- | [[ | + | ==Crystal structure of human RAC3 in complex with CRIB domain of human p21-activated kinase 1 (PAK1)== |
+ | <StructureSection load='2qme' size='340' side='right' caption='[[2qme]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[2qme]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QME OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QME FirstGlance]. <br> | ||
+ | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
+ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2g0n|2g0n]]</td></tr> | ||
+ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAC3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
+ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qme FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qme OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qme RCSB], [http://www.ebi.ac.uk/pdbsum/2qme PDBsum]</span></td></tr> | ||
+ | </table> | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qm/2qme_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | + | ==See Also== | |
- | + | *[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | ||
- | + | ||
- | [[ | + | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] |
Revision as of 06:36, 10 October 2014
Crystal structure of human RAC3 in complex with CRIB domain of human p21-activated kinase 1 (PAK1)
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Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Arrowsmith, C H. | Bunkoczi, G. | Burgess-Brown, N. | Delft, F von. | Doyle, D. | Edwards, A. | Elkins, J M. | Knapp, S. | SGC, Structural Genomics Consortium. | Sundstrom, M. | Ugochukwu, E. | Weigelt, J. | Yang, X. | Allosteric enzyme | Apoptosis | Atp-binding | Cell junction | Cell projection | Crib | Gtp-binding | Gtpase rac3 | Kinase | Lipoprotein | Membrane | Methylation | Nucleotide-binding | P21 rac | Phosphorylation | Prenylation | Ras-related c3 botulinum toxin substrate 3 | Serine/threonine-protein kinase | Sgc | Signaling protein | Signaling protein-transferase complex | Small gtp binding protein | Structural genomic | Structural genomics consortium | Transferase