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1xxr

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[[Image:1xxr.gif|left|200px]]<br /><applet load="1xxr" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1xxr.gif|left|200px]]
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caption="1xxr, resolution 2.00&Aring;" />
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'''Structure of a mannose-specific jacalin-related lectin from Morus Nigra in complex with mannose'''<br />
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{{Structure
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|PDB= 1xxr |SIZE=350|CAPTION= <scene name='initialview01'>1xxr</scene>, resolution 2.00&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''Structure of a mannose-specific jacalin-related lectin from Morus Nigra in complex with mannose'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1XXR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Morus_nigra Morus nigra] with <scene name='pdbligand=MAN:'>MAN</scene>, <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ACY:'>ACY</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXR OCA].
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1XXR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Morus_nigra Morus nigra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXR OCA].
==Reference==
==Reference==
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Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose., Rabijns A, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Rouge P, FEBS J. 2005 Jul;272(14):3725-32. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16008570 16008570]
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Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose., Rabijns A, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Rouge P, FEBS J. 2005 Jul;272(14):3725-32. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16008570 16008570]
[[Category: Morus nigra]]
[[Category: Morus nigra]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tetrameric b-prism fold]]
[[Category: tetrameric b-prism fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:59:45 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:15:52 2008''

Revision as of 13:15, 20 March 2008

Image:1xxr.gif


PDB ID 1xxr

Drag the structure with the mouse to rotate
, resolution 2.00Å
Ligands: , , and
Coordinates: save as pdb, mmCIF, xml



Structure of a mannose-specific jacalin-related lectin from Morus Nigra in complex with mannose


Overview

The structures of MornigaM and the MornigaM-mannose complex have been determined at 1.8 A and 2.0 A resolution, respectively. Both structures adopt the typical beta-prism motif found in other jacalin-related lectins and their tetrameric assembly closely resembles that of jacalin. The carbohydrate-binding cavity of MornigaM readily binds mannose. No major structural rearrangements can be observed in MornigaM upon binding of mannose. These results allow corroboration of the structure-function relationships within the small group of Moraceae lectins.

About this Structure

1XXR is a Single protein structure of sequence from Morus nigra. Full crystallographic information is available from OCA.

Reference

Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose., Rabijns A, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Rouge P, FEBS J. 2005 Jul;272(14):3725-32. PMID:16008570

Page seeded by OCA on Thu Mar 20 15:15:52 2008

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