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1xyq
From Proteopedia
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| - | [[Image:1xyq.gif|left|200px]] | + | [[Image:1xyq.gif|left|200px]] |
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| - | '''NMR structure of the pig prion protein''' | + | {{Structure |
| + | |PDB= 1xyq |SIZE=350|CAPTION= <scene name='initialview01'>1xyq</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= Prnp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 Sus scrofa]) | ||
| + | }} | ||
| + | |||
| + | '''NMR structure of the pig prion protein''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1XYQ is a [ | + | 1XYQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XYQ OCA]. |
==Reference== | ==Reference== | ||
| - | Prion protein NMR structures of cats, dogs, pigs, and sheep., Lysek DA, Schorn C, Nivon LG, Esteve-Moya V, Christen B, Calzolai L, von Schroetter C, Fiorito F, Herrmann T, Guntert P, Wuthrich K, Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):640-5. Epub 2005 Jan 12. PMID:[http:// | + | Prion protein NMR structures of cats, dogs, pigs, and sheep., Lysek DA, Schorn C, Nivon LG, Esteve-Moya V, Christen B, Calzolai L, von Schroetter C, Fiorito F, Herrmann T, Guntert P, Wuthrich K, Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):640-5. Epub 2005 Jan 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15647367 15647367] |
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
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[[Category: tse]] | [[Category: tse]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:16:14 2008'' |
Revision as of 13:16, 20 March 2008
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| Gene: | Prnp (Sus scrofa) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
NMR structure of the pig prion protein
Overview
The NMR structures of the recombinant cellular form of the prion proteins (PrPC) of the cat (Felis catus), dog (Canis familiaris), and pig (Sus scrofa), and of two polymorphic forms of the prion protein from sheep (Ovis aries) are presented. In all of these species, PrPC consists of an N-terminal flexibly extended tail with approximately 100 amino acid residues and a C-terminal globular domain of approximately 100 residues with three alpha-helices and a short antiparallel beta-sheet. Although this global architecture coincides with the previously reported murine, Syrian hamster, bovine, and human PrPC structures, there are local differences between the globular domains of the different species. Because the five newly determined PrPC structures originate from species with widely different transmissible spongiform encephalopathy records, the present data indicate previously uncharacterized possible correlations between local features in PrPC three-dimensional structures and susceptibility of different mammalian species to transmissible spongiform encephalopathies.
About this Structure
1XYQ is a Single protein structure of sequence from Sus scrofa. Full crystallographic information is available from OCA.
Reference
Prion protein NMR structures of cats, dogs, pigs, and sheep., Lysek DA, Schorn C, Nivon LG, Esteve-Moya V, Christen B, Calzolai L, von Schroetter C, Fiorito F, Herrmann T, Guntert P, Wuthrich K, Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):640-5. Epub 2005 Jan 12. PMID:15647367
Page seeded by OCA on Thu Mar 20 15:16:14 2008
Categories: Single protein | Sus scrofa | Herrmann, T. | Lysek, D A. | Schorn, C. | Wuthrich, K. | Nmr | Prion | Prp | Scprp | Tse
