2w3o
From Proteopedia
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{{STRUCTURE_2w3o| PDB=2w3o | SCENE= }} | {{STRUCTURE_2w3o| PDB=2w3o | SCENE= }} | ||
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===CRYSTAL STRUCTURE OF THE HUMAN PNKP FHA DOMAIN IN COMPLEX WITH AN XRCC1-DERIVED PHOSPHOPEPTIDE=== | ===CRYSTAL STRUCTURE OF THE HUMAN PNKP FHA DOMAIN IN COMPLEX WITH AN XRCC1-DERIVED PHOSPHOPEPTIDE=== | ||
+ | {{ABSTRACT_PUBMED_19155274}} | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/XRCC1_HUMAN XRCC1_HUMAN]] Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID:019155274</ref><references group="xtra"/> | + | <ref group="xtra">PMID:019155274</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Ali, A A.E.]] | [[Category: Ali, A A.E.]] |
Revision as of 04:51, 25 March 2013
Contents |
CRYSTAL STRUCTURE OF THE HUMAN PNKP FHA DOMAIN IN COMPLEX WITH AN XRCC1-DERIVED PHOSPHOPEPTIDE
Template:ABSTRACT PUBMED 19155274
Function
[XRCC1_HUMAN] Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.
About this Structure
2w3o is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Ali AA, Jukes RM, Pearl LH, Oliver AW. Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK. Nucleic Acids Res. 2009 Jan 20. PMID:19155274 doi:gkn1086
Categories: Homo sapiens | Ali, A A.E. | Oliver, A W. | Pearl, L H. | Atp-binding | Base excision repair | Dna damage | Dna repair | Fha | Hydrolase | Kinase | Multifunctional enzyme | Nucleotide-binding | Nucleus | Phospho- peptide | Phosphoprotein | Pnkp | Polynucleotide kinase 3' phosphatase | Transferase | Transferase-peptide complex | Transferase/peptide | Xrcc1