2wtw

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Revision as of 21:40, 7 January 2013

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Template:STRUCTURE 2wtw

AURORA-A INHIBITOR STRUCTURE (2ND CRYSTAL FORM)

Template:ABSTRACT PUBMED 20067443

About this Structure

2wtw is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Dodson CA, Kosmopoulou M, Richards MW, Atrash B, Bavetsias V, Blagg J, Bayliss R. Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug design. Biochem J. 2010 Mar 15;427(1):19-28. PMID:20067443 doi:10.1042/BJ20091530