3biz

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Revision as of 22:59, 7 January 2013

Template:STRUCTURE 3biz

Wee1 kinase complex with inhibitor PD331618

Template:ABSTRACT PUBMED 18191399

About this Structure

3biz is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Smaill JB, Lee HH, Palmer BD, Thompson AM, Squire CJ, Baker EN, Booth RJ, Kraker A, Hook K, Denny WA. Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases. Bioorg Med Chem Lett. 2008 Feb 1;18(3):929-33. Epub 2008 Jan 11. PMID:18191399 doi:10.1016/j.bmcl.2007.12.046

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