1ygz
From Proteopedia
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| - | [[Image:1ygz.jpg|left|200px]] | + | [[Image:1ygz.jpg|left|200px]] |
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| - | '''Crystal Structure of Inorganic Pyrophosphatase from Helicobacter pylori''' | + | {{Structure |
| + | |PDB= 1ygz |SIZE=350|CAPTION= <scene name='initialview01'>1ygz</scene>, resolution 2.6Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''Crystal Structure of Inorganic Pyrophosphatase from Helicobacter pylori''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1YGZ is a [ | + | 1YGZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YGZ OCA]. |
==Reference== | ==Reference== | ||
| - | Structure of inorganic pyrophosphatase from Helicobacter pylori., Wu CA, Lokanath NK, Kim DY, Park HJ, Hwang HY, Kim ST, Suh SW, Kim KK, Acta Crystallogr D Biol Crystallogr. 2005 Nov;61(Pt 11):1459-64. Epub 2005, Oct 19. PMID:[http:// | + | Structure of inorganic pyrophosphatase from Helicobacter pylori., Wu CA, Lokanath NK, Kim DY, Park HJ, Hwang HY, Kim ST, Suh SW, Kim KK, Acta Crystallogr D Biol Crystallogr. 2005 Nov;61(Pt 11):1459-64. Epub 2005, Oct 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16239722 16239722] |
[[Category: Helicobacter pylori]] | [[Category: Helicobacter pylori]] | ||
[[Category: Inorganic diphosphatase]] | [[Category: Inorganic diphosphatase]] | ||
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[[Category: hydrolase]] | [[Category: hydrolase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:22:45 2008'' |
Revision as of 13:22, 20 March 2008
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| , resolution 2.6Å | |||||||
|---|---|---|---|---|---|---|---|
| Activity: | Inorganic diphosphatase, with EC number 3.6.1.1 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure of Inorganic Pyrophosphatase from Helicobacter pylori
Overview
Inorganic pyrophosphatase (PPase) is a ubiquitous cytosolic enzyme which catalyzes the hydrolysis of inorganic pyrophosphate (PPi) to orthophosphate (Pi). The crystal structure of inorganic pyrophosphatase from Helicobacter pylori (H-PPase) has been solved by MAD and refined to an R factor of 20.6% at 2.6 A resolution. The crystallographic asymmetric unit contains a homohexameric H-PPase arranged as a dimer of trimers. While most of the structural elements of PPases are highly conserved in H-PPase, some unique structural features are localized in the flexible loops near the active site, suggesting that the structural flexibility of these loops is required for the catalytic efficiency of PPase.
About this Structure
1YGZ is a Single protein structure of sequence from Helicobacter pylori. Full crystallographic information is available from OCA.
Reference
Structure of inorganic pyrophosphatase from Helicobacter pylori., Wu CA, Lokanath NK, Kim DY, Park HJ, Hwang HY, Kim ST, Suh SW, Kim KK, Acta Crystallogr D Biol Crystallogr. 2005 Nov;61(Pt 11):1459-64. Epub 2005, Oct 19. PMID:16239722
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