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3ekk

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Template:STRUCTURE 3ekk

Contents

Insulin receptor kinase complexed with an inhibitor

Template:ABSTRACT PUBMED 19056263

About this Structure

3ekk is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Chamberlain SD, Wilson JW, Deanda F, Patnaik S, Redman AM, Yang B, Shewchuk L, Sabbatini P, Leesnitzer MA, Groy A, Atkins C, Gerding R, Hassell AM, Lei H, Mook RA Jr, Moorthy G, Rowand JL, Stevens KL, Kumar R, Shotwell JB. Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase. Bioorg Med Chem Lett. 2008 Nov 18. PMID:19056263 doi:S0960-894X(08)01424-8

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OCA

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