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3efj

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Revision as of 08:45, 9 January 2013

Image:3efj.png

Template:STRUCTURE 3efj

Structure of c-Met with pyrimidone inhibitor 7

Template:ABSTRACT PUBMED 18763753

About this Structure

3efj is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • D'Angelo ND, Bellon SF, Booker SK, Cheng Y, Coxon A, Dominguez C, Fellows I, Hoffman D, Hungate R, Kaplan-Lefko P, Lee MR, Li C, Liu L, Rainbeau E, Reider PJ, Rex K, Siegmund A, Sun Y, Tasker AS, Xi N, Xu S, Yang Y, Zhang Y, Burgess TL, Dussault I, Kim TS. Design, synthesis, and biological evaluation of potent c-Met inhibitors. J Med Chem. 2008 Sep 25;51(18):5766-79. PMID:18763753 doi:10.1021/jm8006189

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OCA

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