1ym5
From Proteopedia
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| - | [[Image:1ym5.gif|left|200px]] | + | [[Image:1ym5.gif|left|200px]] |
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| - | '''Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily.''' | + | {{Structure |
| + | |PDB= 1ym5 |SIZE=350|CAPTION= <scene name='initialview01'>1ym5</scene>, resolution 2.05Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily.''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1YM5 is a [ | + | 1YM5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YM5 OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily., Liger D, Quevillon-Cheruel S, Sorel I, Bremang M, Blondeau K, Aboulfath I, Janin J, van Tilbeurgh H, Leulliot N, Proteins. 2005 Sep 1;60(4):778-86. PMID:[http:// | + | Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily., Liger D, Quevillon-Cheruel S, Sorel I, Bremang M, Blondeau K, Aboulfath I, Janin J, van Tilbeurgh H, Leulliot N, Proteins. 2005 Sep 1;60(4):778-86. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16021630 16021630] |
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: YSG, Paris-Sud Yeast Structural Genomics.]] | [[Category: YSG, Paris-Sud Yeast Structural Genomics.]] | ||
[[Category: double hot-dog]] | [[Category: double hot-dog]] | ||
| - | [[Category: paris-sud yeast structural | + | [[Category: paris-sud yeast structural genomic]] |
[[Category: phzf enzyme superfamily]] | [[Category: phzf enzyme superfamily]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: ysg]] | [[Category: ysg]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:24:41 2008'' |
Revision as of 13:24, 20 March 2008
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| , resolution 2.05Å | |||||||
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily.
Overview
In the Pseudomonas bacterial genomes, the PhzF proteins are involved in the production of phenazine derivative antibiotic and antifungal compounds. The PhzF superfamily however also encompasses proteins in all genomes from bacteria to eukaryotes, for which no function has been assigned. We have determined the three dimensional crystal structure at 2.05 A resolution of YHI9, the yeast member of the PhzF family. YHI9 has a fold similar to bacterial diaminopimelate epimerase, revealing a bimodular structure with an internal symmetry. Residue conservation identifies a putative active site at the interface between the two domains. Evolution of this protein by gene duplication, gene fusion and domain swapping from an ancestral gene containing the "hot dog" fold, identifies the protein as a "kinked double hot dog" fold.
About this Structure
1YM5 is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily., Liger D, Quevillon-Cheruel S, Sorel I, Bremang M, Blondeau K, Aboulfath I, Janin J, van Tilbeurgh H, Leulliot N, Proteins. 2005 Sep 1;60(4):778-86. PMID:16021630
Page seeded by OCA on Thu Mar 20 15:24:41 2008
Categories: Saccharomyces cerevisiae | Single protein | Aboulfath, I. | Blondeau, K. | Bremang, M. | Janin, J. | Leulliot, N. | Liger, D. | Quevillon-Cheruel, S. | Sorel, I. | Tilbeurgh, H Van. | YSG, Paris-Sud Yeast Structural Genomics. | Double hot-dog | Paris-sud yeast structural genomic | Phzf enzyme superfamily | Structural genomic | Ysg
