4imu

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'''Unreleased structure'''
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{{STRUCTURE_4imu| PDB=4imu | SCENE= }}
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===Structure of rat neuronal nitric oxide synthase in complex with 6,6'-((5-(aminomethyl)-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine)===
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{{ABSTRACT_PUBMED_23451760}}
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The entry 4imu is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/NOS1_RAT NOS1_RAT]] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum.
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Authors: Li, H., Poulos, T.L.
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==About this Structure==
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[[4imu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IMU OCA].
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Description: Structure of rat neuronal nitric oxide synthase in complex with 6,6'-((5-(aminomethyl)-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine)
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[[Category: Rattus norvegicus]]
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[[Category: Li, H.]]
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[[Category: Poulos, T L.]]
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[[Category: Oxidoreductase nitric oxide synthase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 11:20, 24 April 2013

Template:STRUCTURE 4imu

Structure of rat neuronal nitric oxide synthase in complex with 6,6'-((5-(aminomethyl)-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine)

Template:ABSTRACT PUBMED 23451760

Function

[NOS1_RAT] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum.

About this Structure

4imu is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

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