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2m2b

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[[Image:2m2b.jpg|left|200px]]
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==NMR structure of the RRM2 domain of the protein RBM10 from Homo sapiens==
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<StructureSection load='2m2b' size='340' side='right' caption='[[2m2b]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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{{STRUCTURE_2m2b| PDB=2m2b | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2m2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M2B FirstGlance]. <br>
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===NMR structure of the RRM2 domain of the protein RBM10 from Homo sapiens===
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBM10, DXS8237E, GPATC9, GPATCH9, KIAA0122 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m2b RCSB], [http://www.ebi.ac.uk/pdbsum/2m2b PDBsum]</span></td></tr>
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</table>
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==About this Structure==
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== Disease ==
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[[2m2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M2B OCA].
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[[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] TARP syndrome. TARP syndrome (TARPS) [MIM:[http://omim.org/entry/311900 311900]]: A disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20451169</ref>
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== Function ==
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[[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).<ref>PMID:18315527</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Dutta, S K.]]
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[[Category: Dutta, S K]]
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[[Category: Fox, B G.]]
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[[Category: Fox, B G]]
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[[Category: Geralt, M.]]
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[[Category: Geralt, M]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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[[Category: Structural genomic]]
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[[Category: MPP, Mitochondrial Protein Partnership.]]
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[[Category: MPP, Mitochondrial Protein Partnership]]
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[[Category: Makino, S.]]
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[[Category: Makino, S]]
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[[Category: Markley, J L.]]
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[[Category: Markley, J L]]
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[[Category: Misenhiemer, T M.]]
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[[Category: Misenhiemer, T M]]
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[[Category: Serrano, P.]]
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[[Category: Serrano, P]]
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[[Category: TCELL, Partnership for T-Cell Biology.]]
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[[Category: TCELL, Partnership for T-Cell Biology]]
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[[Category: Wrobel, R L.]]
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[[Category: Wrobel, R L]]
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[[Category: Wuthrich, K.]]
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[[Category: Wuthrich, K]]
[[Category: Jcsg]]
[[Category: Jcsg]]
[[Category: Mpp]]
[[Category: Mpp]]

Revision as of 04:51, 22 December 2014

NMR structure of the RRM2 domain of the protein RBM10 from Homo sapiens

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