4gv5
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4gv5| PDB=4gv5 | SCENE= }} | |
| + | ===X-ray structure of crotamine, a cell-penetrating peptide from the Brazilian snake Crotalus durissus terrificus=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/MYX_CRODR MYX_CRODR]] This toxin specifically modifies voltage-gated sodium channels (Nav), it exhibits analgesic activity. Moreover, it actively interacts with lipid membranes (By similarity). It induces severe myonecrosis accompanied by edema and hemorrhage. | ||
| - | + | ==About this Structure== | |
| - | + | [[4gv5]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Crotalus_durissus_ruruima Crotalus durissus ruruima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GV5 OCA]. | |
| - | + | [[Category: Crotalus durissus ruruima]] | |
| + | [[Category: Arni, R K.]] | ||
| + | [[Category: Betzel, C.]] | ||
| + | [[Category: Coronado, M A.]] | ||
| + | [[Category: Gabdulkhakov, A.]] | ||
| + | [[Category: Georgieva, D.]] | ||
| + | [[Category: Murakami, M T.]] | ||
| + | [[Category: Sankaran, B.]] | ||
| + | [[Category: Alpha helix & beta sheet]] | ||
| + | [[Category: Antibacterial peptide]] | ||
| + | [[Category: Extracellular region]] | ||
| + | [[Category: Ion channel inhibitor]] | ||
| + | [[Category: Toxin]] | ||
Revision as of 10:57, 4 September 2013
X-ray structure of crotamine, a cell-penetrating peptide from the Brazilian snake Crotalus durissus terrificus
Function
[MYX_CRODR] This toxin specifically modifies voltage-gated sodium channels (Nav), it exhibits analgesic activity. Moreover, it actively interacts with lipid membranes (By similarity). It induces severe myonecrosis accompanied by edema and hemorrhage.
About this Structure
4gv5 is a 3 chain structure with sequence from Crotalus durissus ruruima. Full crystallographic information is available from OCA.
