1z1y

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[[Image:1z1y.gif|left|200px]]<br /><applet load="1z1y" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1z1y.gif|left|200px]]
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caption="1z1y, resolution 2.000&Aring;" />
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'''Crystal structure of Methylated Pvs25, an ookinete protein from Plasmodium vivax'''<br />
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{{Structure
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|PDB= 1z1y |SIZE=350|CAPTION= <scene name='initialview01'>1z1y</scene>, resolution 2.000&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=YB:YTTERBIUM (III) ION'>YB</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''Crystal structure of Methylated Pvs25, an ookinete protein from Plasmodium vivax'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1Z1Y is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax] with <scene name='pdbligand=YB:'>YB</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1Y OCA].
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1Z1Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1Y OCA].
==Reference==
==Reference==
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The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms., Saxena AK, Singh K, Su HP, Klein MM, Stowers AW, Saul AJ, Long CA, Garboczi DN, Nat Struct Mol Biol. 2006 Jan;13(1):90-1. Epub 2005 Dec 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16327807 16327807]
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The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms., Saxena AK, Singh K, Su HP, Klein MM, Stowers AW, Saul AJ, Long CA, Garboczi DN, Nat Struct Mol Biol. 2006 Jan;13(1):90-1. Epub 2005 Dec 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16327807 16327807]
[[Category: Plasmodium vivax]]
[[Category: Plasmodium vivax]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Su, H P.]]
[[Category: Su, H P.]]
[[Category: YB]]
[[Category: YB]]
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[[Category: four egf-like domains]]
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[[Category: four egf-like domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:11:21 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:30:16 2008''

Revision as of 13:30, 20 March 2008

Image:1z1y.gif


PDB ID 1z1y

Drag the structure with the mouse to rotate
, resolution 2.000Å
Ligands:
Coordinates: save as pdb, mmCIF, xml



Crystal structure of Methylated Pvs25, an ookinete protein from Plasmodium vivax


Overview

P25 and P28 proteins are essential for Plasmodium parasites to infect mosquitoes and are leading candidates for a transmission-blocking malaria vaccine. The Plasmodium vivax P25 is a triangular prism that could tile the parasite surface. The residues forming the triangle are conserved in P25 and P28 from all Plasmodium species. A cocrystal structure shows that a transmission-blocking antibody uses only its heavy chain to bind Pvs25 at a vertex of the triangle.

About this Structure

1Z1Y is a Single protein structure of sequence from Plasmodium vivax. Full crystallographic information is available from OCA.

Reference

The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms., Saxena AK, Singh K, Su HP, Klein MM, Stowers AW, Saul AJ, Long CA, Garboczi DN, Nat Struct Mol Biol. 2006 Jan;13(1):90-1. Epub 2005 Dec 4. PMID:16327807

Page seeded by OCA on Thu Mar 20 15:30:16 2008

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