2m0y
From Proteopedia
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| - | [[Image:2m0y.png|left|200px]] | ||
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{{STRUCTURE_2m0y| PDB=2m0y | SCENE= }} | {{STRUCTURE_2m0y| PDB=2m0y | SCENE= }} | ||
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===Solution structure of the SH3 domain of DOCK180=== | ===Solution structure of the SH3 domain of DOCK180=== | ||
| + | {{ABSTRACT_PUBMED_23239367}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/DOCK1_MOUSE DOCK1_MOUSE]] Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
Revision as of 10:23, 24 April 2013
Solution structure of the SH3 domain of DOCK180
Template:ABSTRACT PUBMED 23239367
Function
[DOCK1_MOUSE] Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (By similarity).
About this Structure
2m0y is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA.
