1z3g

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1z3g.gif|left|200px]]<br /><applet load="1z3g" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1z3g.gif|left|200px]]
-
caption="1z3g, resolution 3.3&Aring;" />
+
 
-
'''Crystal structure of complex between Pvs25 and Fab fragment of malaria transmission blocking antibody 2A8'''<br />
+
{{Structure
 +
|PDB= 1z3g |SIZE=350|CAPTION= <scene name='initialview01'>1z3g</scene>, resolution 3.3&Aring;
 +
|SITE=
 +
|LIGAND=
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''Crystal structure of complex between Pvs25 and Fab fragment of malaria transmission blocking antibody 2A8'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1Z3G is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3G OCA].
+
1Z3G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3G OCA].
==Reference==
==Reference==
-
The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms., Saxena AK, Singh K, Su HP, Klein MM, Stowers AW, Saul AJ, Long CA, Garboczi DN, Nat Struct Mol Biol. 2006 Jan;13(1):90-1. Epub 2005 Dec 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16327807 16327807]
+
The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms., Saxena AK, Singh K, Su HP, Klein MM, Stowers AW, Saul AJ, Long CA, Garboczi DN, Nat Struct Mol Biol. 2006 Jan;13(1):90-1. Epub 2005 Dec 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16327807 16327807]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Plasmodium vivax]]
[[Category: Plasmodium vivax]]
Line 25: Line 34:
[[Category: pvs25]]
[[Category: pvs25]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:11:43 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:30:45 2008''

Revision as of 13:30, 20 March 2008

Image:1z3g.gif


PDB ID 1z3g

Drag the structure with the mouse to rotate
, resolution 3.3Å
Coordinates: save as pdb, mmCIF, xml



Crystal structure of complex between Pvs25 and Fab fragment of malaria transmission blocking antibody 2A8


Overview

P25 and P28 proteins are essential for Plasmodium parasites to infect mosquitoes and are leading candidates for a transmission-blocking malaria vaccine. The Plasmodium vivax P25 is a triangular prism that could tile the parasite surface. The residues forming the triangle are conserved in P25 and P28 from all Plasmodium species. A cocrystal structure shows that a transmission-blocking antibody uses only its heavy chain to bind Pvs25 at a vertex of the triangle.

About this Structure

1Z3G is a Single protein structure of sequence from Mus musculus and Plasmodium vivax. Full crystallographic information is available from OCA.

Reference

The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms., Saxena AK, Singh K, Su HP, Klein MM, Stowers AW, Saul AJ, Long CA, Garboczi DN, Nat Struct Mol Biol. 2006 Jan;13(1):90-1. Epub 2005 Dec 4. PMID:16327807

Page seeded by OCA on Thu Mar 20 15:30:45 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1z3g"
Personal tools