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1z8d

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[[Image:1z8d.gif|left|200px]]<br /><applet load="1z8d" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1z8d.gif|left|200px]]
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caption="1z8d, resolution 2.30&Aring;" />
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'''Crystal Structure of Human Muscle Glycogen Phosphorylase a with AMP and Glucose'''<br />
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{{Structure
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|PDB= 1z8d |SIZE=350|CAPTION= <scene name='initialview01'>1z8d</scene>, resolution 2.30&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=GLC:GLUCOSE'>GLC</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene> and <scene name='pdbligand=ADE:ADENINE'>ADE</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1]
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|GENE= PYGM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal Structure of Human Muscle Glycogen Phosphorylase a with AMP and Glucose'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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1Z8D is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=GLC:'>GLC</scene>, <scene name='pdbligand=AMP:'>AMP</scene> and <scene name='pdbligand=ADE:'>ADE</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8D OCA].
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1Z8D is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8D OCA].
==Reference==
==Reference==
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The crystal structure of human muscle glycogen phosphorylase a with bound glucose and AMP: an intermediate conformation with T-state and R-state features., Lukacs CM, Oikonomakos NG, Crowther RL, Hong LN, Kammlott RU, Levin W, Li S, Liu CM, Lucas-McGady D, Pietranico S, Reik L, Proteins. 2006 Jun 1;63(4):1123-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16523484 16523484]
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The crystal structure of human muscle glycogen phosphorylase a with bound glucose and AMP: an intermediate conformation with T-state and R-state features., Lukacs CM, Oikonomakos NG, Crowther RL, Hong LN, Kammlott RU, Levin W, Li S, Liu CM, Lucas-McGady D, Pietranico S, Reik L, Proteins. 2006 Jun 1;63(4):1123-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16523484 16523484]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphorylase]]
[[Category: Phosphorylase]]
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[[Category: transferase]]
[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:13:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:32:28 2008''

Revision as of 13:32, 20 March 2008

Image:1z8d.gif


PDB ID 1z8d

Drag the structure with the mouse to rotate
, resolution 2.30Å
Ligands: , and
Gene: PYGM (Homo sapiens)
Activity: Phosphorylase, with EC number 2.4.1.1
Coordinates: save as pdb, mmCIF, xml



Crystal Structure of Human Muscle Glycogen Phosphorylase a with AMP and Glucose


Disease

Known disease associated with this structure: McArdle disease OMIM:[608455]

About this Structure

1Z8D is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

The crystal structure of human muscle glycogen phosphorylase a with bound glucose and AMP: an intermediate conformation with T-state and R-state features., Lukacs CM, Oikonomakos NG, Crowther RL, Hong LN, Kammlott RU, Levin W, Li S, Liu CM, Lucas-McGady D, Pietranico S, Reik L, Proteins. 2006 Jun 1;63(4):1123-6. PMID:16523484

Page seeded by OCA on Thu Mar 20 15:32:28 2008

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