4ij6

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'''Unreleased structure'''
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{{STRUCTURE_4ij6| PDB=4ij6 | SCENE= }}
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===Crystal Structure of a Novel-type Phosphoserine Phosphatase Mutant (H9A) from <i>Hydrogenobacter thermophilus</i> TK-6 in Complex with L-phosphoserine===
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{{ABSTRACT_PUBMED_23479726}}
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The entry 4ij6 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/PSPA_HYDTT PSPA_HYDTT]] Catalyzes the dephosphorylation of L-phosphoserine to serine and inorganic phosphate. Is poorly or not active toward D-phosphoserine, DL-phosphothreonine, 3-phosphoglycerate, para-nitrophenylphosphate, and fructose-6-phosphate. Does not display phosphoglycerate mutase activity.
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Authors: Chiba, Y., Horita, S., Ohtsuka, J., Arai, H., Nagata, K., Igarashi, Y., Tanokura, M., Ishii, M.
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==About this Structure==
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[[4ij6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hydrogenobacter_thermophilus_tk-6 Hydrogenobacter thermophilus tk-6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IJ6 OCA].
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Description: Crystal Structure of a Novel-type Phosphoserine Phosphatase Mutant (H9A) from <i>Hydrogenobacter thermophilus</i> TK-6 in Complex with L-phosphoserine
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==Reference==
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<ref group="xtra">PMID:023479726</ref><references group="xtra"/><references/>
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[[Category: Hydrogenobacter thermophilus tk-6]]
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[[Category: Phosphoserine phosphatase]]
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[[Category: Arai, H.]]
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[[Category: Chiba, Y.]]
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[[Category: Horita, S.]]
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[[Category: Igarashi, Y.]]
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[[Category: Ishii, M.]]
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[[Category: Nagata, K.]]
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[[Category: Ohtsuka, J.]]
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[[Category: Tanokura, M.]]
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[[Category: Hydrolase]]
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[[Category: Phosphatase]]

Revision as of 14:04, 10 July 2013

Template:STRUCTURE 4ij6

Contents

Crystal Structure of a Novel-type Phosphoserine Phosphatase Mutant (H9A) from Hydrogenobacter thermophilus TK-6 in Complex with L-phosphoserine

Template:ABSTRACT PUBMED 23479726

Function

[PSPA_HYDTT] Catalyzes the dephosphorylation of L-phosphoserine to serine and inorganic phosphate. Is poorly or not active toward D-phosphoserine, DL-phosphothreonine, 3-phosphoglycerate, para-nitrophenylphosphate, and fructose-6-phosphate. Does not display phosphoglycerate mutase activity.

About this Structure

4ij6 is a 2 chain structure with sequence from Hydrogenobacter thermophilus tk-6. Full crystallographic information is available from OCA.

Reference

  • Chiba Y, Horita S, Ohtsuka J, Arai H, Nagata K, Igarashi Y, Tanokura M, Ishii M. Structural units important for activity of a novel-type phosphoserine phosphatase from Hydrogenobacter thermophilus TK-6 revealed by crystal structure analysis. J Biol Chem. 2013 Apr 19;288(16):11448-58. doi: 10.1074/jbc.M112.449561. Epub, 2013 Mar 11. PMID:23479726 doi:10.1074/jbc.M112.449561

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