1zig
From Proteopedia
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| - | [[Image:1zig.gif|left|200px]] | + | [[Image:1zig.gif|left|200px]] |
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| - | '''GAGA RNA TETRALOOP, NMR, 10 STRUCTURES''' | + | {{Structure |
| + | |PDB= 1zig |SIZE=350|CAPTION= <scene name='initialview01'>1zig</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''GAGA RNA TETRALOOP, NMR, 10 STRUCTURES''' | ||
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==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1ZIG is a [ | + | 1ZIG is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZIG OCA]. |
==Reference== | ==Reference== | ||
| - | A network of heterogeneous hydrogen bonds in GNRA tetraloops., Jucker FM, Heus HA, Yip PF, Moors EH, Pardi A, J Mol Biol. 1996 Dec 20;264(5):968-80. PMID:[http:// | + | A network of heterogeneous hydrogen bonds in GNRA tetraloops., Jucker FM, Heus HA, Yip PF, Moors EH, Pardi A, J Mol Biol. 1996 Dec 20;264(5):968-80. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9000624 9000624] |
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Heus, H A.]] | [[Category: Heus, H A.]] | ||
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[[Category: ribonucleic acid]] | [[Category: ribonucleic acid]] | ||
[[Category: rna]] | [[Category: rna]] | ||
| - | [[Category: | + | [[Category: tetraloop]] |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:35:56 2008'' |
Revision as of 13:35, 20 March 2008
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
GAGA RNA TETRALOOP, NMR, 10 STRUCTURES
Overview
RNA hairpin loops containing a GNRA consensus sequence are the most frequently occurring hairpins in a variety of prokaryotic and eukaryotic RNAs. These tetraloops play important functional roles in RNA folding, in RNA-RNA tertiary interactions and as protein binding sites. Homo and heteronuclear NMR spectroscopy have been used to determine the structures of the most abundant members of the GNRA tetraloop family: the GAGA, GCAA and GAAA loops closed by a C-G base pair. Analysis of the structures of these three hairpin loops reveals a network of heterogeneous hydrogen bonds. The loops contain a G-A base pair, a G base-phosphate hydrogen bond and several 2' OH-base hydrogen bonds. These intramolecular interactions and the extensive base stacking in the loop help explain the high thermodynamic stability and give insight into the diverse biological roles of the GNRA RNA hairpins.
About this Structure
1ZIG is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
A network of heterogeneous hydrogen bonds in GNRA tetraloops., Jucker FM, Heus HA, Yip PF, Moors EH, Pardi A, J Mol Biol. 1996 Dec 20;264(5):968-80. PMID:9000624
Page seeded by OCA on Thu Mar 20 15:35:56 2008
Categories: Protein complex | Heus, H A. | Jucker, F M. | Moors, E. | Pardi, A. | Yip, P F. | Gnra | Hairpin | Ribonucleic acid | Rna | Tetraloop
