1hjz
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 1HJZ is a | + | 1HJZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus] with MES as [http://en.wikipedia.org/wiki/ligand ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1HJZ OCA]. |
==Reference== | ==Reference== | ||
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[[Category: histone macroh2a]] | [[Category: histone macroh2a]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 5 14:05:05 2007'' |
Revision as of 11:59, 5 November 2007
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CRYSTAL STRUCTURE OF AF1521 PROTEIN CONTAINING A MACROH2A DOMAIN
Overview
MacroH2A is an unusual histone H2A variant that has an extensive, C-terminal tail that comprises approximately two thirds of the protein., The C-terminal non-histone domain of macroH2A is also found in a number of, other proteins and has been termed the macro domain. Here we report the, crystal structure to 1.7A of AF1521, a protein consisting of a stand-alone, macro domain from Archaeoglobus fulgidus. The structure has a mixed, alpha/beta fold that closely resembles the N-terminal DNA binding domain, of the Escherichia coli leucine aminopeptidase PepA. The structure also, shows some similarity to members of the P-loop family of nucleotide, hydrolases.
About this Structure
1HJZ is a Single protein structure of sequence from Archaeoglobus fulgidus with MES as ligand. Structure known Active Site: AC1. Full crystallographic information is available from OCA.
Reference
The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A., Allen MD, Buckle AM, Cordell SC, Lowe J, Bycroft M, J Mol Biol. 2003 Jul 11;330(3):503-11. PMID:12842467
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