3ao4

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[[Image:3ao4.png|left|200px]]
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==Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase==
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<StructureSection load='3ao4' size='340' side='right' caption='[[3ao4]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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{{STRUCTURE_3ao4| PDB=3ao4 | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ao4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AO4 FirstGlance]. <br>
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===Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=833:3-(1,3-BENZODIOXOL-5-YL)-1-METHYL-1H-PYRAZOL-5-AMINE'>833</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3l3u|3l3u]], [[1bl3|1bl3]], [[3ovn|3ovn]], [[3ao1|3ao1]], [[3ao2|3ao2]], [[3ao3|3ao3]], [[3ao5|3ao5]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ao4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ao4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ao4 RCSB], [http://www.ebi.ac.uk/pdbsum/3ao4 PDBsum]</span></td></tr>
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[[3ao4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AO4 OCA].
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</table>
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021275048</ref><references group="xtra"/>
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[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Chalmers, D K.]]
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[[Category: Chalmers, D K]]
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[[Category: Headey, S J.]]
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[[Category: Headey, S J]]
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[[Category: Parker, M W.]]
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[[Category: Parker, M W]]
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[[Category: Scanlon, M J.]]
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[[Category: Scanlon, M J]]
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[[Category: Wielens, J.]]
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[[Category: Wielens, J]]
[[Category: Aid]]
[[Category: Aid]]
[[Category: Dna binding]]
[[Category: Dna binding]]

Revision as of 11:02, 20 January 2015

Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase

3ao4, resolution 1.95Å

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