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3d9d

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[[Image:3d9d.png|left|200px]]
 
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{{STRUCTURE_3d9d| PDB=3d9d | SCENE= }}
{{STRUCTURE_3d9d| PDB=3d9d | SCENE= }}
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===Nitroalkane oxidase: mutant D402N crystallized with 1-nitrohexane===
===Nitroalkane oxidase: mutant D402N crystallized with 1-nitrohexane===
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{{ABSTRACT_PUBMED_19265437}}
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{{ABSTRACT_PUBMED_19265437}}
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==Function==
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[[http://www.uniprot.org/uniprot/NAO_FUSOX NAO_FUSOX]] Catalyzes the oxidative denitrification of neutral nitroalkanes, including 3-nitro-2-pentanol, 1-nitropropane, 2-nitropropane, nitroethane and nitrocyclohexane, and may thereby protect the organism against toxic compounds. Has no detectable acyl-CoA dehydrogenase activity.<ref>PMID:11867731</ref> <ref>PMID:22538</ref> <ref>PMID:16430210</ref>
==About this Structure==
==About this Structure==
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[[3d9d]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D9D OCA].
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[[3d9d]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusox Fusox]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D9D OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:019265437</ref><ref group="xtra">PMID:016430210</ref><ref group="xtra">PMID:017994768</ref><references group="xtra"/>
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<ref group="xtra">PMID:019265437</ref><references group="xtra"/><references/>
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[[Category: Fusarium oxysporum]]
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[[Category: Fusox]]
[[Category: Nitroalkane oxidase]]
[[Category: Nitroalkane oxidase]]
[[Category: Bozinovski, D M.]]
[[Category: Bozinovski, D M.]]

Revision as of 06:26, 23 April 2014

Template:STRUCTURE 3d9d

Contents

Nitroalkane oxidase: mutant D402N crystallized with 1-nitrohexane

Template:ABSTRACT PUBMED 19265437

Function

[NAO_FUSOX] Catalyzes the oxidative denitrification of neutral nitroalkanes, including 3-nitro-2-pentanol, 1-nitropropane, 2-nitropropane, nitroethane and nitrocyclohexane, and may thereby protect the organism against toxic compounds. Has no detectable acyl-CoA dehydrogenase activity.[1] [2] [3]

About this Structure

3d9d is a 4 chain structure with sequence from Fusox. Full crystallographic information is available from OCA.

Reference

  • Heroux A, Bozinovski DM, Valley MP, Fitzpatrick PF, Orville AM. Crystal Structures of Intermediates in the Nitroalkane Oxidase Reaction (dagger) (double dagger). Biochemistry. 2009 Mar 27. PMID:19265437 doi:10.1021/bi8023042
  1. ↑ Daubner SC, Gadda G, Valley MP, Fitzpatrick PF. Cloning of nitroalkane oxidase from Fusarium oxysporum identifies a new member of the acyl-CoA dehydrogenase superfamily. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2702-7. Epub 2002 Feb 26. PMID:11867731 doi:http://dx.doi.org/10.1073/pnas.052527799
  2. ↑ Kido T, Hashizume K, Soda K. Purification and properties of nitroalkane oxidase from Fusarium oxysporum. J Bacteriol. 1978 Jan;133(1):53-8. PMID:22538
  3. ↑ Nagpal A, Valley MP, Fitzpatrick PF, Orville AM. Crystal structures of nitroalkane oxidase: insights into the reaction mechanism from a covalent complex of the flavoenzyme trapped during turnover. Biochemistry. 2006 Jan 31;45(4):1138-50. PMID:16430210 doi:10.1021/bi051966w

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