3eos

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Revision as of 13:40, 6 February 2013

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Template:STRUCTURE 3eos

tRNA-guanine transglycosylase in complex with 6-amino-4-{2-[(cyclohexylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

Template:ABSTRACT PUBMED 19894214

About this Structure

3eos is a 1 chain structure with sequence from Zymomonas mobilis. Full crystallographic information is available from OCA.

Reference

• Ritschel T, Kohler PC, Neudert G, Heine A, Diederich F, Klebe G. How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA-Guanine Transglycosylase. ChemMedChem. 2009 Dec;4(12):2012-23. PMID:19894214 doi:10.1002/cmdc.200900343