1zye

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[[Image:1zye.gif|left|200px]]<br /><applet load="1zye" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1zye.gif|left|200px]]
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caption="1zye, resolution 3.30&Aring;" />
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'''Crystal strucutre analysis of Bovine Mitochondrial Peroxiredoxin III'''<br />
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{{Structure
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|PDB= 1zye |SIZE=350|CAPTION= <scene name='initialview01'>1zye</scene>, resolution 3.30&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY= [http://en.wikipedia.org/wiki/Peroxiredoxin Peroxiredoxin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.15 1.11.1.15]
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|GENE=
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}}
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'''Crystal strucutre analysis of Bovine Mitochondrial Peroxiredoxin III'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1ZYE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Active as [http://en.wikipedia.org/wiki/Peroxiredoxin Peroxiredoxin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.15 1.11.1.15] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYE OCA].
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1ZYE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYE OCA].
==Reference==
==Reference==
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Bovine mitochondrial peroxiredoxin III forms a two-ring catenane., Cao Z, Roszak AW, Gourlay LJ, Lindsay JG, Isaacs NW, Structure. 2005 Nov;13(11):1661-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16271889 16271889]
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Bovine mitochondrial peroxiredoxin III forms a two-ring catenane., Cao Z, Roszak AW, Gourlay LJ, Lindsay JG, Isaacs NW, Structure. 2005 Nov;13(11):1661-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16271889 16271889]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Peroxiredoxin]]
[[Category: Peroxiredoxin]]
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[[Category: peroxiredoxin]]
[[Category: peroxiredoxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:20:15 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:41:16 2008''

Revision as of 13:41, 20 March 2008

Image:1zye.gif


PDB ID 1zye

Drag the structure with the mouse to rotate
, resolution 3.30Å
Activity: Peroxiredoxin, with EC number 1.11.1.15
Coordinates: save as pdb, mmCIF, xml



Crystal strucutre analysis of Bovine Mitochondrial Peroxiredoxin III


Overview

A crystal structure is reported for the C168S mutant of a typical 2-Cys peroxiredoxin III (Prx III) from bovine mitochondria at a resolution of 3.3 A. Prx III is present as a two-ring catenane comprising two interlocking dodecameric toroids that are assembled from basic dimeric units. Each ring has an external diameter of 150 A and encompasses a central cavity that is 70 A in width. The concatenated dodecamers are inclined at an angle of 55 degrees, which provides a large contact surface between the rings. Dimer-dimer contacts involved in toroid formation are hydrophobic in nature, whereas the 12 areas of contact between interlocked rings arise from polar interactions. These two major modes of subunit interaction provide important insights into possible mechanisms of catenane formation.

About this Structure

1ZYE is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Bovine mitochondrial peroxiredoxin III forms a two-ring catenane., Cao Z, Roszak AW, Gourlay LJ, Lindsay JG, Isaacs NW, Structure. 2005 Nov;13(11):1661-4. PMID:16271889

Page seeded by OCA on Thu Mar 20 15:41:16 2008

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