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217d

From Proteopedia

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[[Image:217d.gif|left|200px]]<br /><applet load="217d" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:217d.gif|left|200px]]
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caption="217d, resolution 1.700&Aring;" />
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'''CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN'''<br />
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{{Structure
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|PDB= 217d |SIZE=350|CAPTION= <scene name='initialview01'>217d</scene>, resolution 1.700&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=DMY:DISTAMYCIN+A'>DMY</scene> and <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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217D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=DMY:'>DMY</scene> and <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=217D OCA].
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217D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=217D OCA].
==Reference==
==Reference==
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Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7552741 7552741]
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Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7552741 7552741]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Chen, X.]]
[[Category: Chen, X.]]
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[[Category: modified]]
[[Category: modified]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:21:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:42:16 2008''

Revision as of 13:42, 20 March 2008

Image:217d.gif


PDB ID 217d

Drag the structure with the mouse to rotate
, resolution 1.700Å
Ligands: and
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN


Overview

Two DNA-RNA chimers, complexed with DNA minor groove binding drugs, have been observed to adopt the B-form conformation for the first time. Thus, the RNA duplex may assume the B-DNA conformation when interacting with drugs, peptides or proteins.

About this Structure

217D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:7552741

Page seeded by OCA on Thu Mar 20 15:42:16 2008

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