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3f66

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Template:STRUCTURE 3f66

Human c-Met Kinase in complex with quinoxaline inhibitor

Template:ABSTRACT PUBMED 19059779

About this Structure

3f66 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Porter J, Lumb S, Lecomte F, Reuberson J, Foley A, Calmiano M, le Riche K, Edwards H, Delgado J, Franklin RJ, Gascon-Simorte JM, Maloney A, Meier C, Batchelor M. Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase. Bioorg Med Chem Lett. 2009 Jan 15;19(2):397-400. Epub 2008 Nov 21. PMID:19059779 doi:10.1016/j.bmcl.2008.11.062

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