272d
From Proteopedia
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| - | [[Image:272d.jpg|left|200px]] | + | [[Image:272d.jpg|left|200px]] |
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| - | '''PARALLEL AND ANTIPARALLEL (G.GC)2 TRIPLE HELIX FRAGMENTS IN A CRYSTAL STRUCTURE''' | + | {{Structure |
| + | |PDB= 272d |SIZE=350|CAPTION= <scene name='initialview01'>272d</scene>, resolution 2.000Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''PARALLEL AND ANTIPARALLEL (G.GC)2 TRIPLE HELIX FRAGMENTS IN A CRYSTAL STRUCTURE''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 272D is a [ | + | 272D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=272D OCA]. |
==Reference== | ==Reference== | ||
| - | Parallel and antiparallel (G.GC)2 triple helix fragments in a crystal structure., Vlieghe D, Van Meervelt L, Dautant A, Gallois B, Precigoux G, Kennard O, Science. 1996 Sep 20;273(5282):1702-5. PMID:[http:// | + | Parallel and antiparallel (G.GC)2 triple helix fragments in a crystal structure., Vlieghe D, Van Meervelt L, Dautant A, Gallois B, Precigoux G, Kennard O, Science. 1996 Sep 20;273(5282):1702-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8781231 8781231] |
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Dautant, A.]] | [[Category: Dautant, A.]] | ||
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[[Category: double helix]] | [[Category: double helix]] | ||
[[Category: intermolecular base triplet]] | [[Category: intermolecular base triplet]] | ||
| - | [[Category: overhanging | + | [[Category: overhanging base]] |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:43:32 2008'' |
Revision as of 13:43, 20 March 2008
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| , resolution 2.000Å | |||||||
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
PARALLEL AND ANTIPARALLEL (G.GC)2 TRIPLE HELIX FRAGMENTS IN A CRYSTAL STRUCTURE
Overview
Nucleic acid triplexes are formed by sequence-specific interactions between single-stranded polynucleotides and the double helix. These triplexes are implicated in genetic recombination in vivo and have application to areas that include genome analysis and antigene therapy. Despite the importance of the triple helix, only limited high-resolution structural information is available. The x-ray crystal structure of the oligonucleotide d(GGCCAATTGG) is described; it was designed to contain the d(G middle dotGC)2 fragment and thus provide the basic repeat unit of a DNA triple helix. Parameters derived from this crystal structure have made it possible to construct models of both parallel and antiparallel triple helices.
About this Structure
272D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Parallel and antiparallel (G.GC)2 triple helix fragments in a crystal structure., Vlieghe D, Van Meervelt L, Dautant A, Gallois B, Precigoux G, Kennard O, Science. 1996 Sep 20;273(5282):1702-5. PMID:8781231
Page seeded by OCA on Thu Mar 20 15:43:32 2008
