4b8s

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'''Unreleased structure'''
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{{STRUCTURE_4b8s| PDB=4b8s | SCENE= }}
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===Crystal Structure of Thermococcus litoralis ADP-dependent Glucokinase (GK)===
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{{ABSTRACT_PUBMED_23818958}}
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The entry 4b8s is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/GLKA_THELI GLKA_THELI]] Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. Can also use CDP as the phosphoryl group donor and D-glucosamine and D-1,5-anhydroglucitol as the phosphoryl group acceptor.<ref>PMID:11098152</ref>
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Authors: Herrera-Morande, A., Rivas-Pardo, J.A., Fernandez, F.J., Guixe, V., Vega, M.C.
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==About this Structure==
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[[4b8s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermococcus_litoralis Thermococcus litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B8S OCA].
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Description: Crystal Structure of Thermococcus litoralis ADP-dependent Glucokinase (GK)
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==Reference==
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<ref group="xtra">PMID:023818958</ref><references group="xtra"/><references/>
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[[Category: ADP-specific glucokinase]]
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[[Category: Thermococcus litoralis]]
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[[Category: Fernandez, F J.]]
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[[Category: Guixe, V.]]
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[[Category: Herrera-Morande, A.]]
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[[Category: Rivas-Pardo, J A.]]
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[[Category: Vega, M C.]]
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[[Category: Ribokinase superfamily]]
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[[Category: Transferase]]

Revision as of 15:44, 10 July 2013

Template:STRUCTURE 4b8s

Contents

Crystal Structure of Thermococcus litoralis ADP-dependent Glucokinase (GK)

Template:ABSTRACT PUBMED 23818958

Function

[GLKA_THELI] Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. Can also use CDP as the phosphoryl group donor and D-glucosamine and D-1,5-anhydroglucitol as the phosphoryl group acceptor.[1]

About this Structure

4b8s is a 1 chain structure with sequence from Thermococcus litoralis. Full crystallographic information is available from OCA.

Reference

  • Rivas-Pardo JA, Herrera-Morande A, Castro-Fernandez V, Fernandez FJ, Vega MC, Guixe V. Crystal Structure, SAXS and Kinetic Mechanism of Hyperthermophilic ADP-Dependent Glucokinase from Thermococcus litoralis Reveal a Conserved Mechanism for Catalysis. PLoS One. 2013 Jun 20;8(6):e66687. doi: 10.1371/journal.pone.0066687. Print 2013. PMID:23818958 doi:10.1371/journal.pone.0066687
  1. ↑ Koga S, Yoshioka I, Sakuraba H, Takahashi M, Sakasegawa S, Shimizu S, Ohshima T. Biochemical characterization, cloning, and sequencing of ADP-dependent (AMP-forming) glucokinase from two hyperthermophilic archaea, Pyrococcus furiosus and Thermococcus litoralis. J Biochem. 2000 Dec;128(6):1079-85. PMID:11098152

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