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4irb
From Proteopedia
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| - | + | {{STRUCTURE_4irb| PDB=4irb | SCENE= }} | |
| + | ===Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4=== | ||
| + | {{ABSTRACT_PUBMED_23519808}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/UNG_VACCA UNG_VACCA]] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA. | ||
| - | + | ==About this Structure== | |
| + | [[4irb]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRB OCA]. | ||
| - | + | ==Reference== | |
| + | <ref group="xtra">PMID:023519808</ref><references group="xtra"/><references/> | ||
| + | [[Category: Uracil-DNA glycosylase]] | ||
| + | [[Category: Chattopadhyay, D.]] | ||
| + | [[Category: Nuth, M.]] | ||
| + | [[Category: Ricciardi, R P.]] | ||
| + | [[Category: Sartmatova, D.]] | ||
| + | [[Category: Schormann, N.]] | ||
| + | [[Category: Zhukovskaya, N.]] | ||
| + | [[Category: Beta- sheets at n- and c-terminus]] | ||
| + | [[Category: Binding partners a20 and dna]] | ||
| + | [[Category: Component of processivity factor]] | ||
| + | [[Category: Dimeric assembly]] | ||
| + | [[Category: Dna repair hydrolase]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Parallel beta-sheet of 4 strands in the order 2134]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 18:15, 3 March 2014
Contents |
Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4
Template:ABSTRACT PUBMED 23519808
Function
[UNG_VACCA] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA.
About this Structure
4irb is a 4 chain structure. Full crystallographic information is available from OCA.
Reference
- Sartmatova D, Nash T, Schormann N, Nuth M, Ricciardi R, Banerjee S, Chattopadhyay D. Crystallization and preliminary X-ray diffraction analysis of three recombinant mutants of Vaccinia virus uracil DNA glycosylase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1;69(Pt 3):295-301., doi: 10.1107/S1744309113002716. Epub 2013 Feb 23. PMID:23519808 doi:http://dx.doi.org/10.1107/S1744309113002716
Categories: Uracil-DNA glycosylase | Chattopadhyay, D. | Nuth, M. | Ricciardi, R P. | Sartmatova, D. | Schormann, N. | Zhukovskaya, N. | Beta- sheets at n- and c-terminus | Binding partners a20 and dna | Component of processivity factor | Dimeric assembly | Dna repair hydrolase | Hydrolase | Parallel beta-sheet of 4 strands in the order 2134 | Viral protein
