2a5w

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[[Image:2a5w.gif|left|200px]]<br /><applet load="2a5w" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2a5w.gif|left|200px]]
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caption="2a5w, resolution 2.10&Aring;" />
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'''Crystal structure of the oxidized gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus'''<br />
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{{Structure
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|PDB= 2a5w |SIZE=350|CAPTION= <scene name='initialview01'>2a5w</scene>, resolution 2.10&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
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|ACTIVITY=
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|GENE= DsrC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 Archaeoglobus fulgidus DSM 4304])
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}}
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'''Crystal structure of the oxidized gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2A5W is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_dsm_4304 Archaeoglobus fulgidus dsm 4304] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A5W OCA].
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2A5W is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_dsm_4304 Archaeoglobus fulgidus dsm 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A5W OCA].
==Reference==
==Reference==
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X-ray structure of the gamma-subunit of a dissimilatory sulfite reductase: fixed and flexible C-terminal arms., Mander GJ, Weiss MS, Hedderich R, Kahnt J, Ermler U, Warkentin E, FEBS Lett. 2005 Aug 29;579(21):4600-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16098517 16098517]
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X-ray structure of the gamma-subunit of a dissimilatory sulfite reductase: fixed and flexible C-terminal arms., Mander GJ, Weiss MS, Hedderich R, Kahnt J, Ermler U, Warkentin E, FEBS Lett. 2005 Aug 29;579(21):4600-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16098517 16098517]
[[Category: Archaeoglobus fulgidus dsm 4304]]
[[Category: Archaeoglobus fulgidus dsm 4304]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: orthogonal helix bundle]]
[[Category: orthogonal helix bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:23:54 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:45:44 2008''

Revision as of 13:45, 20 March 2008


PDB ID 2a5w

Drag the structure with the mouse to rotate
, resolution 2.10Å
Ligands:
Gene: DsrC (Archaeoglobus fulgidus DSM 4304)
Coordinates: save as pdb, mmCIF, xml



Crystal structure of the oxidized gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus


Overview

The X-ray structure of the gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus was determined at 1.12 and 2.1A resolution, in the two crystal forms named DsrC(nat) and DsrC(ox) the latter being cocrystallized with the oxidizing agent tert-butyl hydroperoxide. The fold corresponds to that of the homologous protein from Pyrobaculum aerophilum but is significantly more compact. The most interesting, highly conserved C-terminal arm adopts a well-defined conformation in A. fulgidus DsrC in contrast to the completely disordered conformation in P. aerophilum DsrC. The functional relevance of both conformations and of a potentially redox-active disulfide bond between the strictly invariant Cys103 and Cys114 are discussed.

About this Structure

2A5W is a Single protein structure of sequence from Archaeoglobus fulgidus dsm 4304. Full crystallographic information is available from OCA.

Reference

X-ray structure of the gamma-subunit of a dissimilatory sulfite reductase: fixed and flexible C-terminal arms., Mander GJ, Weiss MS, Hedderich R, Kahnt J, Ermler U, Warkentin E, FEBS Lett. 2005 Aug 29;579(21):4600-4. PMID:16098517

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