4iqa
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal Structure Analysis of the E228L Mutant of Human CLIC1== | |
| - | + | <StructureSection load='4iqa' size='340' side='right' caption='[[4iqa]], [[Resolution|resolution]] 2.49Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4iqa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IQA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3uvh|3uvh]], [[3p8w|3p8w]]</td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CLIC1, G6, NCC27 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iqa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iqa RCSB], [http://www.ebi.ac.uk/pdbsum/4iqa PDBsum]</span></td></tr> | |
| - | == | + | </table> |
| - | [[4iqa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IQA OCA]. | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN]] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Achilonu, I A | + | [[Category: Achilonu, I A]] |
[[Category: Cross, M O]] | [[Category: Cross, M O]] | ||
| - | [[Category: Dirr, H W | + | [[Category: Dirr, H W]] |
| - | [[Category: Fanucchi, S | + | [[Category: Fanucchi, S]] |
| - | [[Category: Fernandes, M A | + | [[Category: Fernandes, M A]] |
[[Category: Clic]] | [[Category: Clic]] | ||
[[Category: Glutathione transferase]] | [[Category: Glutathione transferase]] | ||
[[Category: Ph salt bridge ion channel]] | [[Category: Ph salt bridge ion channel]] | ||
[[Category: Transport protein]] | [[Category: Transport protein]] | ||
Revision as of 20:29, 25 December 2014
Crystal Structure Analysis of the E228L Mutant of Human CLIC1
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