2y8p
From Proteopedia
(Difference between revisions)
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| - | [[ | + | ==CRYSTAL STRUCTURE OF AN OUTER MEMBRANE-ANCHORED ENDOLYTIC PEPTIDOGLYCAN LYTIC TRANSGLYCOSYLASE (MLTE) FROM ESCHERICHIA COLI== |
| + | <StructureSection load='2y8p' size='340' side='right' caption='[[2y8p]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2y8p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y8P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y8P FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y8p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y8p RCSB], [http://www.ebi.ac.uk/pdbsum/2y8p PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of the first endolytic peptidoglycan lytic transglycosylase MltE from Escherichia coli is reported here. The degradative activity of this enzyme initiates the process of cell wall recycling, which is an integral event in the existence of bacteria. The structure sheds light on how MltE recognizes its substrate, the cell wall peptidoglycan. It also explains the ability of this endolytic enzyme to cleave in the middle of the peptidoglycan chains. Furthermore, the structure reveals how the enzyme is sequestered on the inner leaflet of the outer membrane. | ||
| - | + | High-Resolution Crystal Structure of MltE, an Outer Membrane-Anchored Endolytic Peptidoglycan Lytic Transglycosylase from Escherichia coli.,Artola-Recolons C, Carrasco-Lopez C, Llarrull LI, Kumarasiri M, Lastochkin E, Martinez de Ilarduya I, Meindl K, Uson I, Mobashery S, Hermoso JA Biochemistry. 2011 Apr 5;50(13):2384-2386. Epub 2011 Mar 8. PMID:21341761<ref>PMID:21341761</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | == | + | |
| - | < | + | |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Artola-Recolons, C | + | [[Category: Artola-Recolons, C]] |
| - | [[Category: Carrasco-Lopez, C | + | [[Category: Carrasco-Lopez, C]] |
| - | [[Category: Hermoso, J A | + | [[Category: Hermoso, J A]] |
| - | [[Category: Kumarasiri, M | + | [[Category: Kumarasiri, M]] |
| - | [[Category: Lastochkin, E | + | [[Category: Lastochkin, E]] |
| - | [[Category: Llarrull, L I | + | [[Category: Llarrull, L I]] |
| - | [[Category: Martinez-Ilarduya, I | + | [[Category: Martinez-Ilarduya, I]] |
| - | [[Category: Meindl, K | + | [[Category: Meindl, K]] |
| - | [[Category: Mobashery, S | + | [[Category: Mobashery, S]] |
| - | [[Category: Uson, I | + | [[Category: Uson, I]] |
[[Category: Cell wall biogenesis/degradation]] | [[Category: Cell wall biogenesis/degradation]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
Revision as of 08:32, 26 November 2014
CRYSTAL STRUCTURE OF AN OUTER MEMBRANE-ANCHORED ENDOLYTIC PEPTIDOGLYCAN LYTIC TRANSGLYCOSYLASE (MLTE) FROM ESCHERICHIA COLI
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