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Pyrrolysine
From Proteopedia
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==Occurrence== | ==Occurrence== | ||
| - | Some proteins in methanogenic archaea include '''[[Pyrrolysine|pyrrolysine (Pyl)]]'''. ''Methanosarcina barkeri'' monomethylamine methyltransferase (MtmB, [[1nth]], [[1l2q]]) was the first identified structure containing this amino acid, and in the crystal structure it is identified as BGX, with the rest of the amnio acid identified as LYS202<ref>PMID: 12029132</ref>. Chemically modified forms of pyrrolysine are present in the MtmB structures [[1tv2]], [[1tv3]], and [[1tv4]]<ref>PMID: 15380192</ref>. The [[PDB]] also contains several structures for pyrrolysyl-tRNA synthetase | + | Some proteins in methanogenic archaea include '''[[Pyrrolysine|pyrrolysine (Pyl)]]'''. ''Methanosarcina barkeri'' monomethylamine methyltransferase (MtmB, [[1nth]], [[1l2q]]) was the first identified structure containing this amino acid, and in the crystal structure it is identified as BGX, with the rest of the amnio acid identified as LYS202<ref>PMID: 12029132</ref>. Chemically modified forms of pyrrolysine are present in the MtmB structures [[1tv2]], [[1tv3]], and [[1tv4]]<ref>PMID: 15380192</ref>. The [[PDB]] also contains several structures for pyrrolysyl-tRNA synthetase, including |
Revision as of 00:00, 21 February 2013
Pyrrolysine is a naturally-occurring, genetically encoded amino acid, sometimes called the "22nd amino acid". For more information, please see Pyrrolysine in Wikipedia.
Occurrence
Some proteins in methanogenic archaea include pyrrolysine (Pyl). Methanosarcina barkeri monomethylamine methyltransferase (MtmB, 1nth, 1l2q) was the first identified structure containing this amino acid, and in the crystal structure it is identified as BGX, with the rest of the amnio acid identified as LYS202[1]. Chemically modified forms of pyrrolysine are present in the MtmB structures 1tv2, 1tv3, and 1tv4[2]. The PDB also contains several structures for pyrrolysyl-tRNA synthetase, including
