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3h0y

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Revision as of 15:34, 27 February 2013

Image:3h0y.png

Template:STRUCTURE 3h0y

Aurora A in complex with a bisanilinopyrimidine

Template:ABSTRACT PUBMED 19402633

About this Structure

3h0y is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Aliagas-Martin I, Burdick D, Corson L, Dotson J, Drummond J, Fields C, Huang OW, Hunsaker T, Kleinheinz T, Krueger E, Liang J, Moffat J, Phillips G, Pulk R, Rawson TE, Ultsch M, Walker L, Wiesmann C, Zhang B, Zhu BY, Cochran AG. A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B. J Med Chem. 2009 May 28;52(10):3300-7. PMID:19402633 doi:10.1021/jm9000314

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OCA

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