4h4f
From Proteopedia
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| - | [[Image:4h4f.png|left|200px]] | ||
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{{STRUCTURE_4h4f| PDB=4h4f | SCENE= }} | {{STRUCTURE_4h4f| PDB=4h4f | SCENE= }} | ||
| + | ===Crystal structure of human chymotrypsin C (CTRC) bound to inhibitor eglin c from Hirudo medicinalis=== | ||
| + | {{ABSTRACT_PUBMED_23430245}} | ||
| - | === | + | ==Disease== |
| + | [[http://www.uniprot.org/uniprot/CTRC_HUMAN CTRC_HUMAN]] Hereditary chronic pancreatitis. Note=Genetic variations in CTRC can predispose to chronic pancreatitis by diminishing its protective trypsin-degrading activity. | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/CTRC_HUMAN CTRC_HUMAN]] Has chymotrypsin-type protease activity and hypocalcemic activity. [[http://www.uniprot.org/uniprot/ICIC_HIRME ICIC_HIRME]] Inhibits both elastase and cathepsin G. | ||
==About this Structure== | ==About this Structure== | ||
Revision as of 09:33, 24 April 2013
Contents |
Crystal structure of human chymotrypsin C (CTRC) bound to inhibitor eglin c from Hirudo medicinalis
Template:ABSTRACT PUBMED 23430245
Disease
[CTRC_HUMAN] Hereditary chronic pancreatitis. Note=Genetic variations in CTRC can predispose to chronic pancreatitis by diminishing its protective trypsin-degrading activity.
Function
[CTRC_HUMAN] Has chymotrypsin-type protease activity and hypocalcemic activity. [ICIC_HIRME] Inhibits both elastase and cathepsin G.
About this Structure
4h4f is a 3 chain structure with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
