4hpa

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'''Unreleased structure'''
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{{STRUCTURE_4hpa| PDB=4hpa | SCENE= }}
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===Crystal structure of Nitrophorin 4 from Rhodnius prolixus Complexed with sulfide ion at pH 7.4===
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{{ABSTRACT_PUBMED_23474537}}
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The entry 4hpa is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR]] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).
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Authors: Nishikawa, K., Ogata, H., Knipp, M.
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==About this Structure==
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[[4hpa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhopr Rhopr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPA OCA].
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Description: Crystal structure of Nitrophorin 4 from Rhodnius prolixus Complexed with sulfide ion at pH 7.4
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==Reference==
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<ref group="xtra">PMID:023474537</ref><references group="xtra"/><references/>
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[[Category: Rhopr]]
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[[Category: Knipp, M.]]
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[[Category: Nishikawa, K.]]
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[[Category: Ogata, H.]]
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[[Category: Heme]]
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[[Category: Lipocalin]]
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[[Category: Metal binding protein]]
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[[Category: Nitrophorin]]
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[[Category: Sulfide]]
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[[Category: Transport protein]]

Revision as of 08:45, 19 March 2014

Template:STRUCTURE 4hpa

Contents

Crystal structure of Nitrophorin 4 from Rhodnius prolixus Complexed with sulfide ion at pH 7.4

Template:ABSTRACT PUBMED 23474537

Function

[NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).

About this Structure

4hpa is a 1 chain structure with sequence from Rhopr. Full crystallographic information is available from OCA.

Reference

  • He C, Nishikawa K, Erdem OF, Reijerse E, Ogata H, Lubitz W, Knipp M. Complexes of ferriheme nitrophorin 4 with low-molecular weight thiol(ate)s occurring in blood plasma. J Inorg Biochem. 2013 May;122:38-48. doi: 10.1016/j.jinorgbio.2013.01.012. Epub, 2013 Feb 4. PMID:23474537 doi:http://dx.doi.org/10.1016/j.jinorgbio.2013.01.012

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OCA

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