4hva

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'''Unreleased structure'''
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{{STRUCTURE_4hva| PDB=4hva | SCENE= }}
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===Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6===
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{{ABSTRACT_PUBMED_23227217}}
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The entry 4hva is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
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Authors: Murray, J.M., Steffek, M.
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==About this Structure==
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[[4hva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HVA OCA].
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Description: Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6
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[[Category: Caspase-6]]
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[[Category: Homo sapiens]]
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[[Category: Murray, J M.]]
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[[Category: Steffek, M.]]
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[[Category: Active]]
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[[Category: Caspase]]
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[[Category: Caspase-6]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Protease]]
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[[Category: Ternary complex]]
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[[Category: Uncompetitive inhibition]]
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[[Category: Veid]]

Revision as of 21:43, 10 April 2013

Template:STRUCTURE 4hva

Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6

Template:ABSTRACT PUBMED 23227217

Function

[CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

About this Structure

4hva is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Proteopedia Page Contributors and Editors (what is this?)

OCA

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