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4hva
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4hva| PDB=4hva | SCENE= }} | |
| + | ===Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6=== | ||
| + | {{ABSTRACT_PUBMED_23227217}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. | ||
| - | + | ==About this Structure== | |
| - | + | [[4hva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HVA OCA]. | |
| - | + | [[Category: Caspase-6]] | |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Murray, J M.]] | ||
| + | [[Category: Steffek, M.]] | ||
| + | [[Category: Active]] | ||
| + | [[Category: Caspase]] | ||
| + | [[Category: Caspase-6]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Ternary complex]] | ||
| + | [[Category: Uncompetitive inhibition]] | ||
| + | [[Category: Veid]] | ||
Revision as of 21:43, 10 April 2013
Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6
Template:ABSTRACT PUBMED 23227217
Function
[CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
About this Structure
4hva is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
